Thermal Vein Closure
What is thermal vein closure?
Thermal vein closure has been the mainstay of minimally invasive vein treatment for nearly the past decade. The ClosureFast procedure is performed using a catheter that is equipped with a heating element and connected to a radiofrequency (RF) generator. Prior to activating the heating element, the saphenous compartment, which surrounds the vein, is filled with a liquid referred to as tumescent anesthesia. Tumescent anesthesia acts as a heat sink to protect surrounding tissue from excessive temperatures during treatment.¹
How does thermal vein closure work?
The catheter is inserted into the leg through a single puncture
Tumescent anesthesia is injected into the saphenous compartment
Radiofrequency or laser energy is applied to the heating element
Vein wall collapses from heat-induced collagen denaturation
Is thermal vein closure clinically proven?
Good-quality evidence supports the use of the ClosureFast thermal ablation systems for long-term varicose vein closure. The VeClose study demonstrated complete vein closure in 97.0% of individuals treated with thermal ablation at one year following treatment,ᴬ and additional clinical studies reported similar results.²⁻⁴
Is a thermal vein closure procedure right for me?
 Lohr, J., & Kulwicki, A. (2010). Radiofrequency Ablation: Evolution of a Treatment. Seminars in Vascular Surgery, 23(2), 90–100.
 Morrison, N., Gibson, K., Vasquez, M., Weiss, R., Cher, D., Madsen, M., & Jones, A. (2017). VeClose trial 12-month outcomes of cyanoacrylate closure versus radiofrequency ablation for incompetent great saphenous veins. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 5(3), 321–330.
 Lawaetz, M., Serup, J., Lawaetz, B., Bjoern, L., Blemings, A., Eklof, B., & Rasmussen, L. (2017). Comparison of endovenous ablation techniques, foam sclerotherapy and surgical stripping for great saphenous varicose veins. Extended 5-year follow-up of a RCT. International Angiology, 36(3), 281–288.
 Rasmussen, L., Lawaetz, M., Bjoern, L., Blemings, A., & Eklof, B. (2013). Randomized clinical trial comparing endovenous laser ablation and stripping of the great saphenous vein with clinical and duplex outcome after 5 years. Journal of Vascular Surgery, 58(2), 421–426.
[A] Kaplan-Meir analysis; raw rate of complete closure was 96.8% (92/95 individuals studied with 13 lost to follow-up)